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Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records

BACKGROUND: Vasomotor symptoms (VMS) can often significantly impact women’s quality of life at menopause. In vivo studies have shown that increased neurokinin B (NKB) / neurokinin 3 receptor (NK3R) signalling contributes to VMS, with previous genetic studies implicating the TACR3 gene locus that enc...

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Detalles Bibliográficos
Autores principales: Ruth, Katherine S., Beaumont, Robin N., Locke, Jonathan M., Tyrrell, Jessica, Crandall, Carolyn J., Hawkes, Gareth, Frayling, Timothy M., Prague, Julia K., Patel, Kashyap A., Wood, Andrew R., Weedon, Michael N., Murray, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546673/
https://www.ncbi.nlm.nih.gov/pubmed/37784116
http://dx.doi.org/10.1186/s12920-023-01658-w