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Low-dose xenogeneic mesenchymal stem cells target canine osteoarthritis through systemic immunomodulation and homing

BACKGROUND: As current therapies for canine osteoarthritis (OA) provide mainly symptomatic improvement and fail to address the complex pathology of the disease, mesenchymal stem cells (MSCs) offer a promising biological approach to address both aspects of OA through their immunomodulatory properties...

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Detalles Bibliográficos
Autores principales: Beerts, Charlotte, Broeckx, Sarah Y., Depuydt, Eva, Tack, Liesa, Van Hecke, Lore, Chiers, Koen, Van Brantegem, Leen, Braun, Gabriele, Hellmann, Klaus, de Bouvre, Nathalie, Van Bruaene, Nathalie, De Ryck, Tine, Duchateau, Luc, Van Ryssen, Bernadette, Peremans, Kathelijne, Saunders, Jimmy H., Verhoeven, Geert, Pauwelyn, Glenn, Spaas, Jan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546732/
https://www.ncbi.nlm.nih.gov/pubmed/37789403
http://dx.doi.org/10.1186/s13075-023-03168-7