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The Frequency of Specific KRAS Mutations, and Their Impact on Treatment Choice and Survival, in Patients With Metastatic Colorectal Cancer

BACKGROUND: Patients with metastatic colorectal cancer (mCRC) and KRAS mutations have a poor prognosis, seemingly dependent on the location of the mutation. This multicenter, retrospective, cohort study assessed the frequency and prognostic value of specific KRAS mutation codon locations in mCRC pat...

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Detalles Bibliográficos
Autores principales: Fernández Montes, Ana, Alonso Orduña, Vicente, Asensio Martínez, Elena, Rodríguez Salas, Nuria, Torres, Esperanza, Cacho Lavín, Diego, Rodríguez Alonso, Rosa María, Falcó, Esther, Oliva, Joan Carles, Cirera, Lluis, García Gómez, Jesus, Pericay, Carles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546812/
https://www.ncbi.nlm.nih.gov/pubmed/37141400
http://dx.doi.org/10.1093/oncolo/oyad117