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Impact of Anti-EGFR Therapies on HER2-Positive Metastatic Colorectal Cancer: A Systematic Literature Review and Meta-Analysis of Clinical Outcomes

BACKGROUND: HER2 overexpression/amplification in patients with RAS wild-type (WT) metastatic colorectal cancer (mCRC) may be associated with resistance to standard-of-care anti-EGFR therapies. Given the lack of comprehensive investigations into this association, we assessed the prognostic or predict...

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Detalles Bibliográficos
Autores principales: Bekaii-Saab, Tanios S, Lach, Krzysztof, Hsu, Ling-I, Siadak, Muriel, Stecher, Mike, Ward, James, Beckerman, Rachel, Strickler, John H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546818/
https://www.ncbi.nlm.nih.gov/pubmed/37463037
http://dx.doi.org/10.1093/oncolo/oyad200