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APP(swe) /PS1(ΔE9) mice exhibit low oxygen saturation and alterations of erythrocytes preceding the neuropathology and cognitive deficiency during Alzheimer's disease
AIM: The molecular mechanism underlying Alzheimer's disease (AD) pathologies remains unclear. The brain is extremely sensitive to oxygen deprivation, and brief interruptions in oxygen supply may lead to permanent brain damage. The objective here was to access the red blood cell (RBC) physiologi...
Autores principales: | Wang, Manli, Chen, Xi, Niu, Long, Xu, Jianli, Yu, Hang, Xu, Xiaojiao, Yang, Qiu, Xiang, Yang, Le, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546960/ https://www.ncbi.nlm.nih.gov/pubmed/36883266 http://dx.doi.org/10.1111/cns.14147 |
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