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Integrating gene expression data into a genome-scale metabolic model to identify reprogramming during adaptive evolution
The development of a method for identifying latent reprogramming in gene expression data resulting from adaptive laboratory evolution (ALE) in response to genetic or environmental perturbations has been a challenge. In this study, a method called Metabolic Reprogramming Identifier (MRI), based on th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547208/ https://www.ncbi.nlm.nih.gov/pubmed/37788289 http://dx.doi.org/10.1371/journal.pone.0292433 |