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Neuronal expression in Drosophila of an evolutionarily conserved metallophosphodiesterase reveals pleiotropic roles in longevity and odorant response

Evolutionarily conserved genes often play critical roles in organismal physiology. Here, we describe multiple roles of a previously uncharacterized Class III metallophosphodiesterase in Drosophila, an ortholog of the MPPED1 and MPPED2 proteins expressed in the mammalian brain. dMpped, the product of...

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Detalles Bibliográficos
Autores principales: Gupta, Kriti, Chakrabarti, Sveta, Janardan, Vishnu, Gogia, Nishita, Banerjee, Sanghita, Srinivas, Swarna, Mahishi, Deepthi, Visweswariah, Sandhya S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547211/
https://www.ncbi.nlm.nih.gov/pubmed/37733787
http://dx.doi.org/10.1371/journal.pgen.1010962