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Systematic Review and Meta-analysis: Loss of Response and Need for Dose Escalation of Infliximab and Adalimumab in Ulcerative Colitis

BACKGROUND: Loss of response to infliximab or adalimumab in ulcerative colitis occurs frequently, and dose escalation may aid in regaining clinical benefit. This study aimed to systematically assess the annual loss of response and dose escalation rates for infliximab and adalimumab in ulcerative col...

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Detalles Bibliográficos
Autores principales: Savelkoul, Edo H J, Thomas, Pepijn W A, Derikx, Lauranne A A P, den Broeder, Nathan, Römkens, Tessa E H, Hoentjen, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547237/
https://www.ncbi.nlm.nih.gov/pubmed/36318229
http://dx.doi.org/10.1093/ibd/izac200