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Unraveling the palindromic and nonpalindromic motifs of retroviral integration site sequences by statistical mixture models

A weak palindromic nucleotide motif is the hallmark of retroviral integration site alignments. Given that the majority of target sequences are not palindromic, the current model explains the symmetry by an overlap of the nonpalindromic motif present on one of the half-sites of the sequences. Here, w...

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Detalles Bibliográficos
Autores principales: Miklík, Dalibor, Grim, Jiří, Elleder, Daniel, Hejnar, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547254/
https://www.ncbi.nlm.nih.gov/pubmed/37463751
http://dx.doi.org/10.1101/gr.277694.123