Penalized Model‐Based Unsupervised Phenomapping Unravels Distinctive HFrEF Phenotypes With Improved Outcomes Discrimination From Sacubitril/Valsartan Treatment Independent of MAGGIC Score

BACKGROUND: The angiotensin receptor–neprilysin inhibitor (LCZ696) has emerged as a promising pharmacological intervention against renin–angiotensin system inhibitor in reduced ejection fraction heart failure (HFrEF). Whether the therapeutic benefits may vary among heterogeneous HFrEF subgroups rema...

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Detalles Bibliográficos
Autores principales: Sung, Kuo‐Tzu, Chang, Hung‐Yu, Hsu, Nai‐Wei, Huang, Wen‐Hung, Lin, Yueh‐Hung, Yun, Chun‐Ho, Hsiao, Chih‐Chung, Hsu, Chien‐Yi, Tsai, Shin‐Yi, Chen, Ying‐Ju, Tsai, Cheng‐Ting, Su, Cheng‐Huang, Hung, Ta‐Chuan, Hou, Charles Jia‐Yin, Yeh, Hung‐I, Hung, Chung‐Lieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547272/
https://www.ncbi.nlm.nih.gov/pubmed/37681571
http://dx.doi.org/10.1161/JAHA.122.028860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547272/
https://www.ncbi.nlm.nih.gov/pubmed/37681571
http://dx.doi.org/10.1161/JAHA.122.028860

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