Insulin‐Like Growth Factor 1 Receptor Deficiency Alleviates Angiotensin II–Induced Cardiac Fibrosis Through the Protein Kinase B/Extracellular Signal‐Regulated Kinase/Nuclear Factor‐κB Pathway

BACKGROUND: The renin‐angiotensin system plays a crucial role in the development of heart failure, and Ang II (angiotensin II) acts as the critical effector of the renin‐angiotensin system in regulating cardiac fibrosis. However, the mechanisms of cardiac fibrosis are complex and still not fully und...

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Detalles Bibliográficos
Autores principales: Zhu, Jiafeng, Li, Qian, Sun, Yan, Zhang, Shiyu, Pan, Ruiyan, Xie, Yanguang, Chen, Jinyan, Shi, Lihong, Chen, Yanbo, Sun, Zhipeng, Zhang, Lane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547288/
https://www.ncbi.nlm.nih.gov/pubmed/37721135
http://dx.doi.org/10.1161/JAHA.123.029631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547288/
https://www.ncbi.nlm.nih.gov/pubmed/37721135
http://dx.doi.org/10.1161/JAHA.123.029631

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