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Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

BACKGROUND: Endocardial cells are a major progenitor population that gives rise to heart valves through endocardial cushion formation by endocardial to mesenchymal transformation and the subsequent endocardial cushion remodeling. Genetic variants that affect these developmental processes can lead to...

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Detalles Bibliográficos
Autores principales: Wu, Bingruo, Wu, Brian, Benkaci, Sonia, Shi, Lijie, Lu, Pengfei, Park, Taeju, Morrow, Bernice E., Wang, Yidong, Zhou, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547300/
https://www.ncbi.nlm.nih.gov/pubmed/37702066
http://dx.doi.org/10.1161/JAHA.123.029683