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Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development
BACKGROUND: Endocardial cells are a major progenitor population that gives rise to heart valves through endocardial cushion formation by endocardial to mesenchymal transformation and the subsequent endocardial cushion remodeling. Genetic variants that affect these developmental processes can lead to...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547300/ https://www.ncbi.nlm.nih.gov/pubmed/37702066 http://dx.doi.org/10.1161/JAHA.123.029683 |