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Age‐Associated Changes in Endothelial Transcriptome and Epigenetic Landscapes Correlate With Elevated Risk of Cerebral Microbleeds

BACKGROUND: Stroke is a leading global cause of human death and disability, with advanced aging associated with elevated incidences of stroke. Despite high mortality and morbidity of stroke, the mechanisms leading to blood‐brain barrier dysfunction and development of stroke with age are poorly under...

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Detalles Bibliográficos
Autores principales: Mohan, Kshitij, Gasparoni, Gilles, Salhab, Abdulrahman, Orlich, Michael M., Geffers, Robert, Hoffmann, Steve, Adams, Ralf H., Walter, Jörn, Nordheim, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547332/
https://www.ncbi.nlm.nih.gov/pubmed/37609982
http://dx.doi.org/10.1161/JAHA.123.031044