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CircRNA itchy E3 ubiquitin protein ligase improves mitochondrial dysfunction in sepsis-induced acute kidney injury by targeting microRNA-214-3p/ATP-binding cassette A1 axis

BACKGROUND: Circular RNAs (circRNAs) are promising biomarkers and therapeutic targets for acute kidney injury (AKI). In this study, we investigated the mechanism by which circRNA itchy E3 ubiquitin protein ligase (circ-ITCH) regulates sepsis-induced AKI. METHODS: A sepsis-induced AKI mouse model was...

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Detalles Bibliográficos
Autores principales: Ye, Weidi, Miao, Qi, Xu, Guangxin, Jin, Kai, Li, Xue, Wu, Weidong, Yu, Lina, Yan, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547449/
https://www.ncbi.nlm.nih.gov/pubmed/37782276
http://dx.doi.org/10.1080/0886022X.2023.2261552