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Systems level identification of a matrisome-associated macrophage polarisation state in multi-organ fibrosis

Tissue fibrosis affects multiple organs and involves a master-regulatory role of macrophages which respond to an initial inflammatory insult common in all forms of fibrosis. The recently unravelled multi-organ heterogeneity of macrophages in healthy and fibrotic human disease suggests that macrophag...

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Detalles Bibliográficos
Autores principales: Ouyang, John F, Mishra, Kunal, Xie, Yi, Park, Harry, Huang, Kevin Y, Petretto, Enrico, Behmoaras, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547479/
https://www.ncbi.nlm.nih.gov/pubmed/37706477
http://dx.doi.org/10.7554/eLife.85530