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Mapping pediatric brain tumors to their origins in the developing cerebellum

BACKGROUND: Distinguishing the cellular origins of childhood brain tumors is key for understanding tumor initiation and identifying lineage-restricted, tumor-specific therapeutic targets. Previous strategies to map the cell-of-origin typically involved comparing human tumors to murine embryonal tiss...

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Detalles Bibliográficos
Autores principales: Okonechnikov, Konstantin, Joshi, Piyush, Sepp, Mari, Leiss, Kevin, Sarropoulos, Ioannis, Murat, Florent, Sill, Martin, Beck, Pengbo, Chan, Kenneth Chun-Ho, Korshunov, Andrey, Sah, Felix, Deng, Maximilian Y, Sturm, Dominik, DeSisto, John, Donson, Andrew M, Foreman, Nicholas K, Green, Adam L, Robinson, Giles, Orr, Brent A, Gao, Qingsong, Darrow, Emily, Hadley, Jennifer L, Northcott, Paul A, Gojo, Johannes, Kawauchi, Daisuke, Hovestadt, Volker, Filbin, Mariella G, von Deimling, Andreas, Zuckermann, Marc, Pajtler, Kristian W, Kool, Marcel, Jones, David T W, Jäger, Natalie, Kutscher, Lena M, Kaessmann, Henrik, Pfister, Stefan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547518/
https://www.ncbi.nlm.nih.gov/pubmed/37534924
http://dx.doi.org/10.1093/neuonc/noad124