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Endostatin Inhibits Blood-Retinal Barrier Breakdown in Diabetic Rats by Increasing the Expression of ICAM-1 and VCAM-1 and Decreasing the Expression of VEGF

OBJECTIVE: Endostatin has become the strongest endogenous angiogenesis inhibitor due to suppressing VEGF expression. The purpose of this study was to assess the impact of endostatin on the blood-retinal barrier (BRB) in diabetic rats. METHODS: SD rats were induced to develop diabetes by streptozotoc...

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Detalles Bibliográficos
Autores principales: Zhou, Jinhua, Xie, Zhenggao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547573/
https://www.ncbi.nlm.nih.gov/pubmed/37795476
http://dx.doi.org/10.1155/2022/5105866