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Is the One-Compartment Model with First Order Absorption a Useful Approximation?
PURPOSE: The one-compartment model with first order absorption (ka1C) has been extensively used to fit oral data. But when the disposition parameters of the drug are not available, the bias in the parameter estimates remains unclear. In this paper, the effect of potential misspecification of the are...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547630/ https://www.ncbi.nlm.nih.gov/pubmed/37594592 http://dx.doi.org/10.1007/s11095-023-03582-1 |