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Targeting histone deacetylase-3 blocked epithelial-mesenchymal plasticity and metastatic dissemination in gastric cancer

BACKGROUND AND PURPOSE: Histone deacetylase (HDAC) inhibitors (HDIs) can modulate the epithelial-mesenchymal transition (EMT) progression and inhibit the migration and invasion of cancer cells. Emerging as a novel class of anti-cancer drugs, HDIs are attracted much attention in the field of drug dis...

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Detalles Bibliográficos
Autores principales: Wu, Sheng-Mao, Jan, Yee-Jee, Tsai, Shih-Chuan, Pan, Hung-Chuan, Shen, Chin-Chang, Yang, Cheng-Ning, Lee, Shu-Hua, Liu, Shing-Hwa, Shen, Li-Wei, Chiu, Chien-Shan, Arbiser, Jack L., Meng, Menghsiao, Sheu, Meei-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547655/
https://www.ncbi.nlm.nih.gov/pubmed/34973135
http://dx.doi.org/10.1007/s10565-021-09673-2