Structural insights into the conformational changes of BTR1/SLC4A11 in complex with PIP(2)

BTR1 (SLC4A11) is a NH(3) stimulated H(+) (OH(-)) transporter belonging to the SLC4 family. Dysfunction of BTR1 leads to diseases such as congenital hereditary endothelial dystrophy (CHED) and Fuchs endothelial corneal dystrophy (FECD). However, the mechanistic basis of BTR1 activation by alkaline p...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Yishuo, Zuo, Peng, Chen, Hongyi, Shan, Hui, Wang, Weize, Dai, Zonglin, Xu, He, Chen, Yayu, Liang, Ling, Ding, Dian, Jin, Yan, Yin, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547724/
https://www.ncbi.nlm.nih.gov/pubmed/37788993
http://dx.doi.org/10.1038/s41467-023-41924-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547724/
https://www.ncbi.nlm.nih.gov/pubmed/37788993
http://dx.doi.org/10.1038/s41467-023-41924-0

Ejemplares similares