Cargando…

Structural insights into the conformational changes of BTR1/SLC4A11 in complex with PIP(2)

BTR1 (SLC4A11) is a NH(3) stimulated H(+) (OH(-)) transporter belonging to the SLC4 family. Dysfunction of BTR1 leads to diseases such as congenital hereditary endothelial dystrophy (CHED) and Fuchs endothelial corneal dystrophy (FECD). However, the mechanistic basis of BTR1 activation by alkaline p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Yishuo, Zuo, Peng, Chen, Hongyi, Shan, Hui, Wang, Weize, Dai, Zonglin, Xu, He, Chen, Yayu, Liang, Ling, Ding, Dian, Jin, Yan, Yin, Yuxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547724/ https://www.ncbi.nlm.nih.gov/pubmed/37788993 http://dx.doi.org/10.1038/s41467-023-41924-0

Ejemplares similares

The Brittle Rachis Trait in Species Belonging to the Triticeae and Its Controlling Genes Btr1 and Btr2
por: Zeng, Xiaoxue, et al.
Publicado: (2020)

BTR: training asynchronous Boolean models using single-cell expression data
por: Lim, Chee Yee, et al.
Publicado: (2016)

The Independent Domestication of Timopheev’s Wheat: Insights from Haplotype Analysis of the Brittle rachis 1 (BTR1-A) Gene
por: Nave, Moran, et al.
Publicado: (2021)

Transcription activation by the siderophore sensor Btr is mediated by ligand-dependent stimulation of promoter clearance
por: Gaballa, Ahmed, et al.
Publicado: (2012)

Exploration of Catalytic Selectivity for Aminotransferase (BtrR) Based on Multiple Molecular Dynamics Simulations
por: Liu, Ye, et al.
Publicado: (2019)

Telomere length heterogeneity in ALT cells is maintained by PML-dependent localization of the BTR complex to telomeres
por: Loe, Taylor K., et al.
Publicado: (2020)

Identification of the Conformational transition pathway in PIP(2) Opening Kir Channels
por: Li, Junwei, et al.
Publicado: (2015)

A Buried Thermal Rail (BTR) Technology to Improve Electrothermal Characteristics of Complementary Field-Effect Transistor (CFET)
por: Pan, Zhecheng, et al.
Publicado: (2023)

BspR/BtrA, an Anti-σ Factor, Regulates the Ability of Bordetella bronchiseptica To Cause Cough in Rats
por: Nakamura, Keiji, et al.
Publicado: (2019)

The Ectopic Expression of Btr2 in Aegilops tauschii Switches the Disarticulation Layer From Above to Below the Rachis Node
por: Zeng, Xiaoxue, et al.
Publicado: (2020)

Little PIP, little PIP, let me in
por: LeBrasseur, Nicole
Publicado: (2002)

Slc11 Synapomorphy: A Conserved 3D Framework Articulating Carrier Conformation Switch
por: Cellier, Mathieu F. M.
Publicado: (2023)

PIP(2) promotes conformation-specific dimerization of the EphA2 membrane region
por: Stefanski, Katherine M., et al.
Publicado: (2020)

PIP(2) PIP(2) Hooray for Maxi K(+)
por: Rittenhouse, Ann R.
Publicado: (2008)

Poplar aquaporin PIP1;1 promotes Arabidopsis growth and development
por: Leng, Huani, et al.
Publicado: (2021)

PC, a Novel Oral Insecticidal Toxin from Bacillus bombysepticus Involved in Host Lethality via APN and BtR-175
por: Lin, Ping, et al.
Publicado: (2015)

The Efficiency of the BTR-Pen System in Removing Different Types of Broken Instruments from Root Canals and Its Effect on the Fracture Resistance of Roots
por: Dulundu, Merve, et al.
Publicado: (2022)

Shape shifting: The multiple conformational substates of the PTEN N‐terminal PIP(2) ‐binding domain
por: Dawson, Jennifer E., et al.
Publicado: (2022)

Structural insights into GIRK2 channel modulation by cholesterol and PIP(2)
por: Mathiharan, Yamuna Kalyani, et al.
Publicado: (2021)

Molecular basis for assembly of the shieldin complex and its implications for NHEJ
por: Liang, Ling, et al.
Publicado: (2020)

Sticking to PIP(2)
por: Tuma, Rabiya
Publicado: (2004)

PIP(2) in endocytosis
por: Williams, Ruth
Publicado: (2007)

PIPs propel phagosomes
por: Short, Ben
Publicado: (2010)

The topoisomerase 3 zinc finger domain cooperates with the RMI1 scaffold to promote stable association of the BTR complex to recombination intermediates in the Caenorhabditis elegans germline
por: Dello Stritto, Maria Rosaria, et al.
Publicado: (2022)

Heterotetramerization of Plant PIP1 and PIP2 Aquaporins Is an Evolutionary Ancient Feature to Guide PIP1 Plasma Membrane Localization and Function
por: Bienert, Manuela D., et al.
Publicado: (2018)

Identification of multiple substrate binding sites in SLC4 transporters in the outward-facing conformation: Insights into the transport mechanism
por: Zhekova, Hristina R., et al.
Publicado: (2021)

Transition between conformational states of the TREK-1 K2P channel promoted by interaction with PIP(2)
por: Panasawatwong, Adisorn, et al.
Publicado: (2022)

Segregation of PIP2 and PIP3 into distinct nanoscale regions within the plasma membrane
por: Wang, Jie, et al.
Publicado: (2012)

Striking a balance: PIP(2) and PIP(3) signaling in neuronal health and disease
por: Tariq, Kamran, et al.
Publicado: (2021)

A Systematic Approach to Review of in vitro Methods in Brain Tumour Research (SAToRI-BTR): Development of a Preliminary Checklist for Evaluating Quality and Human Relevance
por: Bracher, Mike, et al.
Publicado: (2020)

Altered gene expression in slc4a11(−/−) mouse cornea highlights SLC4A11 roles
por: Alvarez, Bernardo V., et al.
Publicado: (2021)

The secreted PAMP-induced peptide StPIP1_1 activates immune responses in potato
por: Nietzschmann, Linda, et al.
Publicado: (2023)

Status of PIP2 at FNAL
por: Pozdeyev, Eduard
Publicado: (2019)

Bringing PIPs to root tips
por: LeBrasseur, Nicole
Publicado: (2005)

Analysis of pip and pp multiplicities
por: Pajares, C, et al.
Publicado: (1977)

ASCOT pips SARS at the post
Publicado: (2003)

Conformational rearrangements in the second voltage sensor domain switch PIP(2)- and voltage-gating modes in two-pore channels
por: Shimomura, Takushi, et al.
Publicado: (2023)

ACLY is the novel signaling target of PIP(2)/PIP(3) and Lyn in acute myeloid leukemia
por: Basappa, Johnvesly, et al.
Publicado: (2020)

Novel Molecular Signatures in the PIP4K/PIP5K Family of Proteins Specific for Different Isozymes and Subfamilies Provide Important Insights into the Evolutionary Divergence of this Protein Family
por: Khadka, Bijendra, et al.
Publicado: (2019)

The pip1s Quintuple Mutants Demonstrate the Essential Roles of PIP1s in the Plant Growth and Development of Arabidopsis
por: Wang, Xing, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_d3c7it326lbuc3j74p5qub43mr