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The ascending limb of the cocaine unit dose–response function in rats as an experimental artifact
The cocaine unit dose–response function is an inverted U with the ascending and descending limbs representing the positive and rate limiting cocaine effects, respectively. Higher fixed ratio (FR) schedules and/or time-out periods make the ascending limb more prominent. Alternatively, a pharmacokinet...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547744/ https://www.ncbi.nlm.nih.gov/pubmed/37789064 http://dx.doi.org/10.1038/s41598-023-43506-y |