Cargando…
KaScape: a sequencing-based method for global characterization of protein‒DNA binding affinity
It is difficult to exhaustively screen all possible DNA binding sequences for a given transcription factor (TF). Here, we developed the KaScape method, in which TFs bind to all possible DNA sequences in the same DNA pool where DNA sequences are prepared by randomized oligo synthesis and the random l...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547764/ https://www.ncbi.nlm.nih.gov/pubmed/37789131 http://dx.doi.org/10.1038/s41598-023-43426-x |