Differential gene expression analysis based on linear mixed model corrects false positive inflation for studying quantitative traits

Differential gene expression (DGE) analysis has been widely employed to identify genes expressed differentially with respect to a trait of interest using RNA sequencing (RNA-Seq) data. Recent RNA-Seq data with large samples pose challenges to existing DGE methods, which were mainly developed for dic...

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Detalles Bibliográficos
Autores principales: Tang, Shizhen, Buchman, Aron S., Wang, Yanling, Avey, Denis, Xu, Jishu, Tasaki, Shinya, Bennett, David A., Zheng, Qi, Yang, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547771/
https://www.ncbi.nlm.nih.gov/pubmed/37789141
http://dx.doi.org/10.1038/s41598-023-43686-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547771/
https://www.ncbi.nlm.nih.gov/pubmed/37789141
http://dx.doi.org/10.1038/s41598-023-43686-7

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