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Differential gene expression analysis based on linear mixed model corrects false positive inflation for studying quantitative traits
Differential gene expression (DGE) analysis has been widely employed to identify genes expressed differentially with respect to a trait of interest using RNA sequencing (RNA-Seq) data. Recent RNA-Seq data with large samples pose challenges to existing DGE methods, which were mainly developed for dic...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547771/ https://www.ncbi.nlm.nih.gov/pubmed/37789141 http://dx.doi.org/10.1038/s41598-023-43686-7 |