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Exploring the role of esketamine in alleviating depressive symptoms in mice via the PGC-1α/irisin/ERK1/2 signaling pathway

Esketamine provides an immediate and noticeable antidepressant effect, although the underlying molecular processes are yet unclear. Irisin induced by aerobic exercise has been implicated in the alleviation of depressive symptoms, whether irisin expression responds to the administration of esketamine...

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Detalles Bibliográficos
Autores principales: Hu, Na, Chen, Xuemei, Chen, Chengchuan, Liu, Xing, Yi, Peng, Xu, Tianhao, Jia, Jing, Feng, Jianguo, Zhang, Chunxiang, Wang, Xiaobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547795/
https://www.ncbi.nlm.nih.gov/pubmed/37789092
http://dx.doi.org/10.1038/s41598-023-43684-9