A spatially specified systems pharmacology therapy for axonal recovery after injury

There are no known drugs or drug combinations that promote substantial central nervous system axonal regeneration after injury. We used systems pharmacology approaches to model pathways underlying axonal growth and identify a four-drug combination that regulates multiple subcellular processes in the...

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Detalles Bibliográficos
Autores principales: Siddiq, Mustafa M., Johnson, Nicholas P., Zorina, Yana, Yadaw, Arjun Singh, Toro, Carlos A., Hansen, Jens, Rabinovich, Vera, Gregorich, Sarah M., Xiong, Yuguang, Tolentino, Rosa E., Hannila, Sari S., Kaplan, Ehud, Blitzer, Robert D., Filbin, Marie T., Cardozo, Christopher P., Passaglia, Christopher L., Iyengar, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547904/
https://www.ncbi.nlm.nih.gov/pubmed/37799971
http://dx.doi.org/10.3389/fphar.2023.1225759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547904/
https://www.ncbi.nlm.nih.gov/pubmed/37799971
http://dx.doi.org/10.3389/fphar.2023.1225759

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