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A spatially specified systems pharmacology therapy for axonal recovery after injury
There are no known drugs or drug combinations that promote substantial central nervous system axonal regeneration after injury. We used systems pharmacology approaches to model pathways underlying axonal growth and identify a four-drug combination that regulates multiple subcellular processes in the...
Autores principales: | Siddiq, Mustafa M., Johnson, Nicholas P., Zorina, Yana, Yadaw, Arjun Singh, Toro, Carlos A., Hansen, Jens, Rabinovich, Vera, Gregorich, Sarah M., Xiong, Yuguang, Tolentino, Rosa E., Hannila, Sari S., Kaplan, Ehud, Blitzer, Robert D., Filbin, Marie T., Cardozo, Christopher P., Passaglia, Christopher L., Iyengar, Ravi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547904/ https://www.ncbi.nlm.nih.gov/pubmed/37799971 http://dx.doi.org/10.3389/fphar.2023.1225759 |
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