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Arf6 as a therapeutic target: Structure, mechanism, and inhibitors

ADP-ribosylation factor 6 (Arf6), a small G-protein of the Ras superfamily, plays pivotal roles in multiple cellular events, including exocytosis, endocytosis, actin remodeling, plasma membrane reorganization and vesicular transport. Arf6 regulates the progression of cancer through the activation of...

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Detalles Bibliográficos
Autores principales: Sun, Dejuan, Guo, Yuanyuan, Tang, Piyu, Li, Hua, Chen, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547916/
https://www.ncbi.nlm.nih.gov/pubmed/37799386
http://dx.doi.org/10.1016/j.apsb.2023.06.008