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Preparation of human primary macrophages to study the polarization from monocyte-derived macrophages to pro- or anti-inflammatory macrophages at biomaterial interface in vitro

BACKGROUND/PURPOSE: Testing of dental materials when in contact with innate immune cells has been so far hindered by the lack of proper in vitro models. Human primary monocyte-derived macrophages (MDMs) would be an excellent option to this aim. However, the inability to detach them from the tissue c...

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Detalles Bibliográficos
Autores principales: Parisi, Ludovica, Bianchi, Massimiliano Giovanni, Ghezzi, Benedetta, Maurizi, Eleonora, Macaluso, Guido Maria, Bussolati, Ovidio, Lumetti, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Dental Sciences of the Republic of China 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547954/
https://www.ncbi.nlm.nih.gov/pubmed/37799917
http://dx.doi.org/10.1016/j.jds.2023.01.020