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Intron retention decreases METTL3 expression by inhibiting mRNA export to the cytoplasm
Methyltransferase-like 3 (METTL3), a key component of the m(6)A methyltransferase complex, regulates the splicing, nuclear transport, stability, and translation of its target genes. However, the mechanism underlying the regulation of METTL3 expression by alternative splicing (AS) remains unknown. We...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547966/ https://www.ncbi.nlm.nih.gov/pubmed/37357537 http://dx.doi.org/10.5483/BMBRep.2023-0069 |