AR-A014418, a glycogen synthase kinase-3β inhibitor, mitigates lipopolysaccharide-induced inflammation in rat dental pulp stem cells via NLR family pyrin domain containing 3 inflammasome impairment

BACKGROUND/PURPOSE: Cell pyroptosis and gingival inflammation have been implicated in periodontitis progression. Our previous study revealed that AR-A014418, a pharmacological inhibitor of glycogen synthase kinase-3β (GSK-3β), can enhance the migratory and osteogenic differentiation abilities of rat...

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Detalles Bibliográficos
Autores principales: Xie, Huilan, Lin, Yi, Fang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Dental Sciences of the Republic of China 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548004/
https://www.ncbi.nlm.nih.gov/pubmed/37799857
http://dx.doi.org/10.1016/j.jds.2023.03.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548004/
https://www.ncbi.nlm.nih.gov/pubmed/37799857
http://dx.doi.org/10.1016/j.jds.2023.03.010

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