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Lineage commitment of dermal fibroblast progenitors is controlled by Kdm6b‐mediated chromatin demethylation

Dermal Fibroblast Progenitors (DFPs) differentiate into distinct fibroblast lineages during skin development. However, the epigenetic mechanisms that regulate DFP differentiation are not known. Our objective was to use multimodal single‐cell approaches, epigenetic assays, and allografting techniques...

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Detalles Bibliográficos
Autores principales: Phan, Quan M, Salz, Lucia, Kindl, Sam S, Lopez, Jayden S, Thompson, Sean M, Makkar, Jasson, Driskell, Iwona M, Driskell, Ryan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548174/
https://www.ncbi.nlm.nih.gov/pubmed/37602956
http://dx.doi.org/10.15252/embj.2023113880