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ER stress induces caspase‐2‐tBID‐GSDME‐dependent cell death in neurons lytically infected with herpes simplex virus type 2

Neurotropic viruses, including herpes simplex virus (HSV) types 1 and 2, have the capacity to infect neurons and can cause severe diseases. This is associated with neuronal cell death, which may contribute to morbidity or even mortality if the infection is not controlled. However, the mechanistic de...

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Detalles Bibliográficos
Autores principales: Ren, Fanghui, Narita, Ryo, Rashidi, Ahmad S, Fruhwürth, Stefanie, Gao, Zongliang, Bak, Rasmus O, Thomsen, Martin K, Verjans, Georges MGM, Reinert, Line S, Paludan, Søren R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548179/
https://www.ncbi.nlm.nih.gov/pubmed/37646198
http://dx.doi.org/10.15252/embj.2022113118