EGFR and PI3K/m-TOR inhibitors: design, microwave assisted synthesis and anticancer activity of thiazole–coumarin hybrids

A series of thiazoline and thiazolidinone-based 4-hydroxycoumarin derivatives were synthesized using both conventional synthesis procedures and microwave-assisted techniques. The new compounds were evaluated for their cytotoxic effect against three human cancer cell lines; MCF-7, HCT-116 and HepG2 a...

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Detalles Bibliográficos
Autores principales: Batran, Rasha Z., Ahmed, Eman Y., Awad, Hanem M., Ali, Korany A., Abdel Latif, Nehad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548181/
https://www.ncbi.nlm.nih.gov/pubmed/37800132
http://dx.doi.org/10.1039/d3ra03483f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548181/
https://www.ncbi.nlm.nih.gov/pubmed/37800132
http://dx.doi.org/10.1039/d3ra03483f

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