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Modulation of intestinal IL-37 expression and its impact on the epithelial innate immune response and barrier integrity

BACKGROUND AND AIMS: Intestinal epithelial cells separate the luminal flora from lamina propria immune cells and regulate innate immune responses in the gut. An imbalance of the mucosal immune response and disrupted intestinal barrier integrity contribute to the evolution of inflammatory bowel disea...

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Detalles Bibliográficos
Autores principales: Kröhn, Laura, Azabdaftari, Aline, Heuberger, Julian, Hudert, Christian, Zilbauer, Matthias, Breiderhoff, Tilman, Bufler, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548260/
https://www.ncbi.nlm.nih.gov/pubmed/37799712
http://dx.doi.org/10.3389/fimmu.2023.1261666