Direct conversion of amino acids to oxetanol bioisosteres via photoredox catalysis

Carboxylic acids are an important structural feature in many drugs, but are associated with a number of unfavorable pharmacological properties. To address this problem, carboxylic acids can be replaced with bioisosteric mimics that interact similarly with biological targets but avoid these liabiliti...

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Detalles Bibliográficos
Autores principales: Delos Reyes, Avelyn Mae V., Nieves Escobar, Christopher S., Muñoz, Alberto, Huffman, Maya I., Tan, Derek S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548506/
https://www.ncbi.nlm.nih.gov/pubmed/37799988
http://dx.doi.org/10.1039/d3sc00936j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548506/
https://www.ncbi.nlm.nih.gov/pubmed/37799988
http://dx.doi.org/10.1039/d3sc00936j

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