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Decreased expression of GEM in osteoarthritis cartilage regulates chondrogenic differentiation via Wnt/β-catenin signaling

BACKGROUND: GEM (GTP-binding protein overexpressed in skeletal muscle) is one of the atypical small GTPase subfamily members recently identified as a regulator of cell differentiation. Abnormal chondrogenesis coupled with an imbalance in the turnover of cartilaginous matrix formation is highly relev...

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Detalles Bibliográficos
Autores principales: Gan, Lu, Deng, Zhonghao, Wei, Yiran, Li, Hongfang, Zhao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548561/
https://www.ncbi.nlm.nih.gov/pubmed/37794464
http://dx.doi.org/10.1186/s13018-023-04236-z