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It is not all about the alpha: elevated expression of p53β variants is associated with lower probability of survival in a retrospective melanoma cohort

BACKGROUND: Melanoma is the deadliest type of skin cancer and despite improvements in treatment outcomes, melanoma claimed 57,043 lives in 2020. In most malignancies, p53 mutation rates are above 50% and provide prognostic indications. However, in melanoma where less than a quarter of cases harbour...

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Detalles Bibliográficos
Autores principales: Groen, Kira, Steffens Reinhardt, Luiza, Bourdon, Jean-Christophe, Avery-Kiejda, Kelly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548590/
https://www.ncbi.nlm.nih.gov/pubmed/37794430
http://dx.doi.org/10.1186/s12935-023-03083-6