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Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress

BACKGROUND: Cerebral amyloid angiopathy (CAA) is a devastating condition common in patients with Alzheimer’s disease but also observed in the general population. Vascular oxidative stress and neurovascular dysfunction have been implicated in CAA but the cellular source of reactive oxygen species (RO...

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Detalles Bibliográficos
Autores principales: Uekawa, Ken, Hattori, Yorito, Ahn, Sung Ji, Seo, James, Casey, Nicole, Anfray, Antoine, Zhou, Ping, Luo, Wenjie, Anrather, Josef, Park, Laibaik, Iadecola, Costantino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548599/
https://www.ncbi.nlm.nih.gov/pubmed/37789345
http://dx.doi.org/10.1186/s13024-023-00660-1