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Graph regularized non-negative matrix factorization with [Formula: see text] norm regularization terms for drug–target interactions prediction

BACKGROUND: Identifying drug–target interactions (DTIs) plays a key role in drug development. Traditional wet experiments to identify DTIs are costly and time consuming. Effective computational methods to predict DTIs are useful to speed up the process of drug discovery. A variety of non-negativity...

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Detalles Bibliográficos
Autores principales: Zhang, Junjun, Xie, Minzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548602/
https://www.ncbi.nlm.nih.gov/pubmed/37789278
http://dx.doi.org/10.1186/s12859-023-05496-6