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Graph regularized non-negative matrix factorization with [Formula: see text] norm regularization terms for drug–target interactions prediction
BACKGROUND: Identifying drug–target interactions (DTIs) plays a key role in drug development. Traditional wet experiments to identify DTIs are costly and time consuming. Effective computational methods to predict DTIs are useful to speed up the process of drug discovery. A variety of non-negativity...
Autores principales: | Zhang, Junjun, Xie, Minzhu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548602/ https://www.ncbi.nlm.nih.gov/pubmed/37789278 http://dx.doi.org/10.1186/s12859-023-05496-6 |
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