Identification of a novel NPM1 mutation in acute myeloid leukemia

Nucleophosmin (NPM1) is a widely expressed nucleocytoplasmic shuttling protein with prominent nucleolar localization. It is estimated that 25–35% of adult patients with acute myeloid leukemia (AML) carry NPM1 mutations. The classic NPM1 type A mutation occurs in exon 12, which accounts for 75–80% of...

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Detalles Bibliográficos
Autores principales: Yao, Yiyi, Lin, Xiangjie, Wang, Chen, Gu, Ying, Jin, Jie, Zhu, Yinghui, Wang, Huafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548603/
https://www.ncbi.nlm.nih.gov/pubmed/37794441
http://dx.doi.org/10.1186/s40164-023-00449-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548603/
https://www.ncbi.nlm.nih.gov/pubmed/37794441
http://dx.doi.org/10.1186/s40164-023-00449-4

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