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Bacillus Calmette-Guérin vaccination as defense against SARS-CoV-2 (BADAS): a randomized controlled trial to protect healthcare workers in the USA by enhanced trained immune responses

BACKGROUND: A large epidemic, such as that observed with SARS-CoV-2, seriously challenges available hospital capacity, and this would be augmented by infection of healthcare workers (HCW). Bacillus Calmette-Guérin (BCG) is a vaccine against tuberculosis, with protective non-specific effects against...

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Detalles Bibliográficos
Autores principales: DiNardo, Andrew R., Arditi, Moshe, Kamat, Ashish M., Koster, Kent J., Carrero, Santiago, Nishiguchi, Tomoki, Lebedev, Maxim, Benjamin, Aaron B., Avalos, Pablo, Lozano, Marisa, Moule, Madeleine G., McCune, Brittany, Herron, Baysia, Ladki, Malik, Sheikh, Daanish, Spears, Matthew, Herrejon, Ivan A., Dodge, Courtney, Kumar, Sathish, Hutchison, Robert W., Ofili, Theresa U., Opperman, Lynne A., Bernard, Jessica A., Lerner, Seth P., Udeani, George, Neal, Gabriel, Netea, Mihai G., Cirillo, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548680/
https://www.ncbi.nlm.nih.gov/pubmed/37794431
http://dx.doi.org/10.1186/s13063-023-07662-w