Sources of bias and limitations of thrombinography: inner filter effect and substrate depletion at the edge of failure algorithm

BACKGROUND: Fluorogenic thrombin generation (TG) is a global hemostasis assay that provides an overall representation of hemostasis potential. However, the accurate detection of thrombin activity in plasma may be affected by artifacts inherent to the assay-associated fluorogenic substrate. The signi...

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Detalles Bibliográficos
Autores principales: Jackson, Joseph W., Longstaff, Colin, Woodle, Samuel A., Chang, William C., Ovanesov, Mikhail V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548689/
https://www.ncbi.nlm.nih.gov/pubmed/37794418
http://dx.doi.org/10.1186/s12959-023-00549-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548689/
https://www.ncbi.nlm.nih.gov/pubmed/37794418
http://dx.doi.org/10.1186/s12959-023-00549-5

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