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Sources of bias and limitations of thrombinography: inner filter effect and substrate depletion at the edge of failure algorithm

BACKGROUND: Fluorogenic thrombin generation (TG) is a global hemostasis assay that provides an overall representation of hemostasis potential. However, the accurate detection of thrombin activity in plasma may be affected by artifacts inherent to the assay-associated fluorogenic substrate. The signi...

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Detalles Bibliográficos
Autores principales:	Jackson, Joseph W., Longstaff, Colin, Woodle, Samuel A., Chang, William C., Ovanesov, Mikhail V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548689/ https://www.ncbi.nlm.nih.gov/pubmed/37794418 http://dx.doi.org/10.1186/s12959-023-00549-5

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