The loss of B7-H4 expression in breast cancer cells escaping from T cell cytotoxicity contributes to epithelial-to-mesenchymal transition

BACKGROUND: B7 homology 4 (B7-H4), a potential target for cancer therapy, has been demonstrated to inhibit T cell cytotoxicity in the early stages of breast cancer. However, B7-H4 manipulating breast tumor immune microenvironment (TIME) in the tumor progression remains unknown. METHODS: We engineere...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Linlin, Wu, Jichun, Ruan, Mei, Xiao, Yonglei, Lan, Hailin, Wu, Qiongwen, Yu, Chen-Wei, Zhang, Qiuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548745/
https://www.ncbi.nlm.nih.gov/pubmed/37794509
http://dx.doi.org/10.1186/s13058-023-01721-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548745/
https://www.ncbi.nlm.nih.gov/pubmed/37794509
http://dx.doi.org/10.1186/s13058-023-01721-5

Ejemplares similares