Dissociation of Cohesin from Chromosome Arms and Loss of Arm Cohesion during Early Mitosis Depends on Phosphorylation of SA2

Cohesin is a protein complex that is required to hold sister chromatids together. Cleavage of the Scc1 subunit of cohesin by the protease separase releases the complex from chromosomes and thereby enables the separation of sister chromatids in anaphase. In vertebrate cells, the bulk of cohesin disso...

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Detalles Bibliográficos
Autores principales: Hauf, Silke, Roitinger, Elisabeth, Koch, Birgit, Dittrich, Christina M, Mechtler, Karl, Peters, Jan-Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1054881/
https://www.ncbi.nlm.nih.gov/pubmed/15737063
http://dx.doi.org/10.1371/journal.pbio.0030069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1054881/
https://www.ncbi.nlm.nih.gov/pubmed/15737063
http://dx.doi.org/10.1371/journal.pbio.0030069

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