Shugoshin Prevents Dissociation of Cohesin from Centromeres During Mitosis in Vertebrate Cells

Cohesion between sister chromatids is essential for their bi-orientation on mitotic spindles. It is mediated by a multisubunit complex called cohesin. In yeast, proteolytic cleavage of cohesin's α kleisin subunit at the onset of anaphase removes cohesin from both centromeres and chromosome arms...

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Detalles Bibliográficos
Autores principales: McGuinness, Barry E, Hirota, Toru, Kudo, Nobuaki R, Peters, Jan-Michael, Nasmyth, Kim
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1054882/
https://www.ncbi.nlm.nih.gov/pubmed/15737064
http://dx.doi.org/10.1371/journal.pbio.0030086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1054882/
https://www.ncbi.nlm.nih.gov/pubmed/15737064
http://dx.doi.org/10.1371/journal.pbio.0030086

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