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Shugoshin Prevents Dissociation of Cohesin from Centromeres During Mitosis in Vertebrate Cells
Cohesion between sister chromatids is essential for their bi-orientation on mitotic spindles. It is mediated by a multisubunit complex called cohesin. In yeast, proteolytic cleavage of cohesin's α kleisin subunit at the onset of anaphase removes cohesin from both centromeres and chromosome arms...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1054882/ https://www.ncbi.nlm.nih.gov/pubmed/15737064 http://dx.doi.org/10.1371/journal.pbio.0030086 |